BDBM362038 (S)-3-(8-cyano-2-(1-((2,6-diamino-5-cyanopyrimidin-4-yl)amino)ethyl)-6-fluoro-4-oxoquinazolin-3(4H)-yl)benzamide::US10221197, Compound 31
SMILES NC(=O)c1cccc(c1)-n1c(nc2c(cc(F)cc2c1=O)C#N)[C@@H](Nc1nc(N)nc(N)c1C#N)C1CC1
InChI Key InChIKey=TUPUGWIROIFGAB-IBGZPJMESA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 362038
Affinity DataIC50: 2.10E+4nMAssay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIP3 for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Gilead Sciences
US Patent
Gilead Sciences
US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Gilead Sciences
US Patent
Gilead Sciences
US Patent