BDBM362038 (S)-3-(8-cyano-2-(1-((2,6-diamino-5-cyanopyrimidin-4-yl)amino)ethyl)-6-fluoro-4-oxoquinazolin-3(4H)-yl)benzamide::US10221197, Compound 31

SMILES NC(=O)c1cccc(c1)-n1c(nc2c(cc(F)cc2c1=O)C#N)[C@@H](Nc1nc(N)nc(N)c1C#N)C1CC1

InChI Key InChIKey=TUPUGWIROIFGAB-IBGZPJMESA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 362038   

TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Human)
Gilead Sciences

US Patent
LigandPNGBDBM362038((S)-3-(8-cyano-2-(1-((2,6-diamino-5-cyanopyrimidin...)
Affinity DataIC50:  2.10E+4nMAssay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIP3 for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM362038((S)-3-(8-cyano-2-(1-((2,6-diamino-5-cyanopyrimidin...)
Affinity DataIC50:  1.10E+6nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM362038((S)-3-(8-cyano-2-(1-((2,6-diamino-5-cyanopyrimidin...)
Affinity DataIC50:  2.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent