BDBM368566 (6,6-difluoro-2-azaspiro [3,3]heptan-2-yl)-[6- (1H-pyrazolo[4,3-b] pyridin- 3-ylamino)-1- naphthyl]methanone::US10227343, Example 167

SMILES FC1(F)CC2(CN(C2)C(=O)c2cccc3cc(Nc4n[nH]c5cccnc45)ccc23)C1

InChI Key InChIKey=IEKMUFOGEFGIMF-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 368566   

TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University

US Patent
LigandChemical structure of BindingDB Monomer ID 368566BDBM368566((6,6-difluoro-2-azaspiro [3,3]heptan-2-yl)-[6- (1H...)
Affinity DataEC50:  413nMAssay Description:The disclosed compounds and compositions can be evaluated for their ability to act as a potentiator of metabotropic glutamate receptor activity, in p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent