BDBM369943 (R)—N-(1-(1-(1H-Indazol-5-yl)-3-methyl-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl)-3-methyl-1-oxobutan-2-yl)-2-fluoro-5-methylbenzamide::US10233182, Example 56

SMILES CC(C)[C@@H](NC(=O)c1cc(C)ccc1F)C(=O)N1CCC2(CC1)N(C(=O)N(C)C2=O)c1ccc2[nH]ncc2c1

InChI Key InChIKey=BDMKXRAWQIQRRY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 369943   

TargetAutotaxin(Human)
X-Rx

US Patent
LigandChemical structure of BindingDB Monomer ID 369943BDBM369943((R)—N-(1-(1-(1H-Indazol-5-yl)-3-methyl-2,4-di...)
Affinity DataIC50: 500nMAssay Description:The efficacy of the Examples described herein, as inhibitors of ATX are demonstrated and confirmed by pharmacological in vitro assays. The following ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent