BDBM371574 4-chloro-5-[[1-[(4,5-dimethyl-1H-imidazol-2-yl)methyl]-3-piperidyl]amino]-2-methyl-pyridazin-3-one::US10239861, Example 54

SMILES Cc1nc(CN2CCCC(C2)Nc2cnn(C)c(=O)c2Cl)[nH]c1C

InChI Key InChIKey=LNYHILMLCLOKHM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 371574   

TargetHistone acetyltransferase KAT2B(Human)
Genetech

US Patent
LigandChemical structure of BindingDB Monomer ID 371574BDBM371574(4-chloro-5-[[1-[(4,5-dimethyl-1H-imidazol-2-yl)met...)
Affinity DataIC50: 1.44E+3nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent