BDBM374668 3-((S)-1-((3R,4S)-1-(1-((R)-1-(4-Chloro-2-fluorophenyl)ethyl)-3-methyl-1H-pyrazolo[3,4-b]pyrazin-6-yl)-3-methylpiperidin-4-yl)pyrrolidin-2-yl)propanoic acid 2,2,2-trifluoroacetate::US10246462, Example 49
SMILES C[C@H](c1ccc(Cl)cc1F)n1nc(C)c2ncc(nc12)N1CCC([C@H](C)C1)N1CCC[C@H]1CCC(O)=O
InChI Key InChIKey=SIEJRLDGKHLLJJ-BKWPFJTKSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 374668
Affinity DataIC50: 300nMAssay Description:To measure binding of 125I-TARC or 125I-MDC to cells expressing CCR4 (e.g., CEM cells (e.g., ATCC HB-12624)), the 125I-TARC or 125I-MDC is diluted to...More data for this Ligand-Target Pair