BDBM375187 6-chloro-3-[(1S)-1-({4-[1-(oxan-2-yl)-1H-::US10253015, Compound I-47

SMILES C[C@H](Nc1cc(-c2ccnn2C2CCCCO2)ccn1)c1cc2cc(Cl)ccc2[nH]c1=O

InChI Key InChIKey=ROBMPVUHFWUUAF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 375187   

LigandChemical structure of BindingDB Monomer ID 375187BDBM375187(6-chloro-3-[(1S)-1-({4-[1-(oxan-2-yl)-1H- | US1025...)
Affinity DataIC50: 550nMAssay Description:Assays were performed in a 384-well black plate. An aliquot of 250 nL of compound was incubated with 10 μL of 30 nM IDH1-R132H or 10 nM IDH1-R13...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 375187BDBM375187(6-chloro-3-[(1S)-1-({4-[1-(oxan-2-yl)-1H- | US1025...)
Affinity DataIC50: 550nMAssay Description:Assays were performed in a 384-well black plate. An aliquot of 250 nL of compound was incubated with 10 μL of 30 nM IDH1-R132H or 10 nM IDH1-R13...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent