BDBM380553 1-{trans-4-[(6- methylquinazolin- 4- yl)amino]cyclo- hexyl}azetidin-3-ol::US9926330, 2-6

SMILES Cc1ccc2ncnc(N[C@H]3CC[C@@H](CC3)N3CC(O)C3)c2c1

InChI Key InChIKey=FLJWSNRBBRDETB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 380553   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 380553BDBM380553(US9926330, 2-6 | 1-{trans-4-[(6- methylquinazolin-...)
Affinity DataIC50: 2.35E+3nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent