BDBM389024 4-[5-({(3R)-1-[(2R)-2- hydroxypropyl]piperidin-3- yl}methoxy)-8-(3-methyl-2-oxo-2,3- dihydro-1,3-benzoxazol-6- yl)imidazo[1,2-c]pyrimidin-7- yl]benzonitrile::US10800779, Example 133::US11401272, Example 133::US9944647, Example 133
SMILES C[C@@H](O)CN1CCC[C@@H](COc2nc(-c3ccc(cc3)C#N)c(-c3ccc4n(C)c(=O)oc4c3)c3nccn23)C1
InChI Key InChIKey=HRTYQIKYUNOAOG-TZIWHRDSSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 389024
Affinity DataIC50: 275nMAssay Description:LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
Affinity DataIC50: 275nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
Affinity DataIC50: 275nMAssay Description:LANCE LSD1/KDM1A demethylase assay—10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair