BDBM389024 4-[5-({(3R)-1-[(2R)-2- hydroxypropyl]piperidin-3- yl}methoxy)-8-(3-methyl-2-oxo-2,3- dihydro-1,3-benzoxazol-6- yl)imidazo[1,2-c]pyrimidin-7- yl]benzonitrile::US10800779, Example 133::US11401272, Example 133::US9944647, Example 133

SMILES C[C@@H](O)CN1CCC[C@@H](COc2nc(-c3ccc(cc3)C#N)c(-c3ccc4n(C)c(=O)oc4c3)c3nccn23)C1

InChI Key InChIKey=HRTYQIKYUNOAOG-TZIWHRDSSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 389024   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM389024(4-[5-({(3R)-1-[(2R)-2- hydroxypropyl]piperidin-3- ...)
Affinity DataIC50:  275nMAssay Description:LANCE LSD1/KDM1A demethylase assay-10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM389024(4-[5-({(3R)-1-[(2R)-2- hydroxypropyl]piperidin-3- ...)
Affinity DataIC50:  275nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM389024(4-[5-({(3R)-1-[(2R)-2- hydroxypropyl]piperidin-3- ...)
Affinity DataIC50:  275nMAssay Description:LANCE LSD1/KDM1A demethylase assay—10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent