BDBM392023 US10301272, Example 6/21
SMILES CC(C)(C)NS(=O)(=O)c1ccc(-c2sc(nc2CC2CCCCC2)C(=O)NN2CCS(=O)(=O)CC2)c(Cl)c1Cl
InChI Key InChIKey=SPDRPVKEOQMNTA-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 392023
TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Homo sapiens (Human))
Phenex Pharmaceuticals
US Patent
Phenex Pharmaceuticals
US Patent
Affinity DataIC50: 158nMAssay Description:Determination of a ligand mediated Gal4 promoter driven transactivation to quantify ligand binding to RORγ was performed as follows: DNA encodin...More data for this Ligand-Target Pair
TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Homo sapiens (Human))
Phenex Pharmaceuticals
US Patent
Phenex Pharmaceuticals
US Patent
Affinity DataIC50: 2nMAssay Description:Cells were incubated for additional 16 h before renilla (REN) luciferase activities were measured sequentially in the same cell extract using a Dual-...More data for this Ligand-Target Pair
TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Homo sapiens (Human))
Phenex Pharmaceuticals
US Patent
Phenex Pharmaceuticals
US Patent
Affinity DataIC50: 2nMAssay Description:Cells were incubated for additional 16 h before firefly (FF) luciferase activities were measured sequentially in the same cell extract using a Dual-L...More data for this Ligand-Target Pair