BDBM403441 (6R,9S)- or (6S,9R)- 4-(4-chloro-2- fluorophenyl)-6,7,8,9- tetrahydro-5H-6,9- epoxycyclo- hepta[b]pyridine-2- carboxamide::US10335399, Example 1-3B::US10806724, Example 1-3B

SMILES NC(=O)c1cc(c2[C@@H]3CC[C@@H](O3)c2n1)-c1ccc(Cl)cc1F

InChI Key InChIKey=FJXVLWXBRGYNDB-QWHCGFSZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 403441   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM403441((6R,9S)- or (6S,9R)- 4-(4-chloro-2- fluorophenyl)-...)
Affinity DataIC50:  12nMAssay Description:The utility of the compounds of the invention as an inhibitor of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM403441((6R,9S)- or (6S,9R)- 4-(4-chloro-2- fluorophenyl)-...)
Affinity DataIC50:  12nMAssay Description:The utility of the compounds of the invention as an inhibitor of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent