BDBM403475 (R)- or (S)-2- ((difluoro- methoxy)methyl)- 5-(2- methylthiazol-5- yl)-3,4-dihydro- 2H-pyrano[2,3- b]pyridine-7- carboxamide::US10335399, Example 3-3B::US10806724, Example 3-3B

SMILES Cc1ncc(s1)-c1cc(nc2O[C@H](COC(F)F)CCc12)C(N)=O

InChI Key InChIKey=YGJQQANQKRRDCJ-QMMMGPOBSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 403475   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM403475((R)- or (S)-2- ((difluoro- methoxy)methyl)- 5-(2- ...)
Affinity DataIC50:  2.52E+3nMAssay Description:The utility of the compounds of the invention as an inhibitor of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM403475((R)- or (S)-2- ((difluoro- methoxy)methyl)- 5-(2- ...)
Affinity DataIC50:  2.52E+3nMAssay Description:The utility of the compounds of the invention as an inhibitor of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent