BDBM408227 N-(2-(4-(1-(quinolin-3-yl)ethyl)piperazin-1-yl)pyrimidin-5-yl)acetamide::US10336775, Example 131

SMILES CC(N1CCN(CC1)c1ncc(NC(C)=O)cn1)c1cnc2ccccc2c1

InChI Key InChIKey=XRNHPDFIDMUNEG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 408227   

TargetProtein O-GlcNAcase(Human)
Asceneuron

US Patent
LigandChemical structure of BindingDB Monomer ID 408227BDBM408227(N-(2-(4-(1-(quinolin-3-yl)ethyl)piperazin-1-yl)pyr...)
Affinity DataIC50: 5.50E+3nMAssay Description:5 μl of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent