BDBM408276 1-(1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)ethyl)-4-(3-methoxyphenyl)piperazine::US10336775, Example 200::US11046712, No 200

SMILES COc1cccc(n1)N1CCN(CC1)C(C)c1ccc2OCCOc2c1

InChI Key InChIKey=DZTAFDVMBYMDTJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 408276   

TargetProtein O-GlcNAcase(Human)
Asceneuron

US Patent
LigandChemical structure of BindingDB Monomer ID 408276BDBM408276(1-(1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)ethyl)-4...)
Affinity DataIC50: 125nMAssay Description:5 μl of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent

TargetProtein O-GlcNAcase(Human)
Asceneuron

US Patent
LigandChemical structure of BindingDB Monomer ID 408276BDBM408276(1-(1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)ethyl)-4...)
Affinity DataIC50: 125nMAssay Description:5 μI of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2021
Entry Details
US Patent