BDBM408481 2-benzyl-4-ethynyl-6- methoxypyrimidine::US10358435, Example 3

SMILES COc1cc(nc(Cc2ccccc2)n1)C#C

InChI Key InChIKey=VPQMZDWISNNZEG-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 408481   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 408481BDBM408481(2-benzyl-4-ethynyl-6- methoxypyrimidine | US103584...)
Affinity DataKi:  112nMAssay Description:In a typical experiment the PDE2 inhibitory activity of the compounds of the present invention was determined in accordance with the following experi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent