BDBM416533 3-cyclopropyl-N-(4-(methylsulfonyl)benzyl)-2-(4-(trifluoromethyl)benzyl)-3H-imidazo[4,5-b]pyridine-6-carboxamide::US10301261, Compound AB-2::US10829448, Compound AB-2

SMILES CS(=O)(=O)c1ccc(CNC(=O)c2cnc3n(C4CC4)c(Cc4ccc(cc4)C(F)(F)F)nc3c2)cc1

InChI Key InChIKey=OLAIHGARTVTVNO-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 416533   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM416533(3-cyclopropyl-N-(4-(methylsulfonyl)benzyl)-2-(4-(t...)
Affinity DataKi:  550nMAssay Description:Compounds described herein were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-ligand (RL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM416533(3-cyclopropyl-N-(4-(methylsulfonyl)benzyl)-2-(4-(t...)
Affinity DataKi:  550nMAssay Description:Compounds described herein were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-ligand (RL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent