BDBM417390 US10457654, Example 242
SMILES Fc1cc(N[C@H]2CC[C@@H](C[C@@H]2N2CCCC2)c2cccc(c2)C(F)(F)F)c(Cl)cc1S(=O)(=O)Nc1ccncn1
InChI Key InChIKey=GYRVYEANGPSPFD-OEOAZWSVSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 417390
Affinity DataIC50: 0.182nMAssay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Affinity DataIC50: 0.428nMAssay Description:Preparation of membranes containing recombinantly expressed sodium channels: Following the procedure described in Example 243A, and making modificati...More data for this Ligand-Target Pair