BDBM418856 N-[2-({[2-({4-[(1S)-1- aminoethyl]phenyl}amino)-5- (trifluoromethyl)pyrimidin-4- yl]amino}methyl)pyridin-3-yl]-N- methylmethane-sulfonamide (356), hydrochloride salt::US10450297, Example 356

SMILES C[C@H](N)c1ccc(Nc2ncc(c(NCc3ncccc3N(C)S(C)(=O)=O)n2)C(F)(F)F)cc1

InChI Key InChIKey=RRPARVPNVHUBQG-ZDUSSCGKSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 418856   

TargetFocal adhesion kinase 1 [410-689](Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM418856(N-[2-({[2-({4-[(1S)-1- aminoethyl]phenyl}amino)-5-...)
Affinity DataIC50:  0.593nMAssay Description:The in vitro activity of the compounds of the compounds of the invention may be determined by the following procedure. More particularly, the followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent