BDBM422087 US10508103, Embodiment 46
SMILES CC[C@H](NC(=O)[C@H](C)NC)C(=O)N1CC(F)(F)C[C@H]1Cc1c([nH]c2cc(F)ccc12)-c1nc2cc(F)ccc2n1C[C@@H]1CC(F)(F)CN1C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)C
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 422087
TargetBaculoviral IAP repeat-containing protein 2 [253-363](Homo sapiens (Human))
Medshine Discovery
US Patent
Medshine Discovery
US Patent
Affinity DataIC50: <10nMAssay Description:1) Affinity of compounds listed in table to cIAP1-BIR3, Ciap2-BIR3, XIAP-BIR3 was tested referring to Nikolovska-Colesks, Z. et.Al. (Analytical Bioch...More data for this Ligand-Target Pair
Affinity DataEC50: 55nMAssay Description:First day:Dilution of Compounds: 1) tested compounds were added into DMSO to give parent liquor (10 mM); 2) reference compound Birinapant (32 &...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:1) Affinity of compounds listed in table to cIAP1-BIR3, Ciap2-BIR3, XIAP-BIR3 was tested referring to Nikolovska-Colesks, Z. et.Al. (Analytical Bioch...More data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 3 [238-349](Homo sapiens (Human))
Medshine Discovery
US Patent
Medshine Discovery
US Patent
Affinity DataIC50: 55nMAssay Description:1) Affinity of compounds listed in table to cIAP1-BIR3, Ciap2-BIR3, XIAP-BIR3 was tested referring to Nikolovska-Colesks, Z. et.Al. (Analytical Bioch...More data for this Ligand-Target Pair