BDBM426747 1-(3-(5-amino-3-(4-((4-methoxypyridin-2- yl)oxy)phenyl)imidazo[1,5-c]pyrimidin-1- yl)pyrrolidin-1-yl)prop-2-en-1-one::US10544106, Compound C210::US11208388, Example 212

SMILES COc1ccnc(Oc2ccc(cc2)-c2nc(C3CCN(C3)C(=O)C=C)c3ccnc(N)n23)c1

InChI Key InChIKey=UHWSPGOKTOEDFE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 426747   

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 426747BDBM426747(1-(3-(5-amino-3-(4-((4-methoxypyridin-2- yl)oxy)ph...)
Affinity DataIC50: 100nMAssay Description:To determine IC50 of a compound against a kinase, a series of concentrations of the compound were tested for the inhibition. IC50 was calculated by p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 426747BDBM426747(1-(3-(5-amino-3-(4-((4-methoxypyridin-2- yl)oxy)ph...)
Affinity DataIC50: 100nMAssay Description:To determine IC50 of a compound against a kinase, a series of concentrations of the compound were tested for the inhibition. IC50 was calculated by p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent