BDBM426765 4-(1-(1-acryloylpyrrolidin-3-yl)-5-amino- imidazo[1,5-c]pyrimidin-3-yl)-N-(4- methoxypyridin-2-yl)benzamide::US10544106, Compound C240::US11208388, Example 240

SMILES COc1ccnc(NC(=O)c2ccc(cc2)-c2nc(C3CCN(C3)C(=O)C=C)c3ccnc(N)n23)c1

InChI Key InChIKey=CYWGEKAUNFSQTK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 426765   

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 426765BDBM426765(4-(1-(1-acryloylpyrrolidin-3-yl)-5-amino- imidazo[...)
Affinity DataIC50: 100nMAssay Description:To determine IC50 of a compound against a kinase, a series of concentrations of the compound were tested for the inhibition. IC50 was calculated by p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2022
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Neupharma

US Patent
LigandChemical structure of BindingDB Monomer ID 426765BDBM426765(4-(1-(1-acryloylpyrrolidin-3-yl)-5-amino- imidazo[...)
Affinity DataIC50: 100nMAssay Description:To determine IC50 of a compound against a kinase, a series of concentrations of the compound were tested for the inhibition. IC50 was calculated by p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent