BDBM438340 Methyl 5-[4-chloro-5-fluoro-2-oxo-1-[2-oxo-2-(2,2,2-trifluoroethylamino)ethyl]spiro[indole-3,4′-piperidine]-1′-carbonyl]-1H-indazole-3-carboxylate::US10618897, Example 161

SMILES COC(=O)c1n[nH]c2ccc(cc12)C(=O)N1CCC2(CC1)C(=O)N(CC(=O)NCC(F)(F)F)c1ccc(F)c(Cl)c21

InChI Key InChIKey=BKQZQLVYUUYQPL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 438340   

TargetEpithelial discoidin domain-containing receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 438340BDBM438340(Methyl 5-[4-chloro-5-fluoro-2-oxo-1-[2-oxo-2-(2,2,...)
Affinity DataIC50: 264nMAssay Description:An in vitro binding competition assay was performed to evaluate the effect of the compounds of present invention on DDR1 protein.Binding Competition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2020
Entry Details
US Patent