BDBM444725 (S)-1-(3-(3-(4-(1-phenylvinyl)phenyl)-1H- pyrazolo [4,3-c]pyridin-1-yl)piperidin-1-yl)prop-2-en- 1-one::US10662187, Compound 95::US10793566, Compound 95

SMILES C=CC(=O)N1CCCC(C1)n1nc(-c2ccc(cc2)C(=C)c2ccccc2)c2cnccc12

InChI Key InChIKey=NTAPTJYDGYBNTR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 444725   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Zibo Biopolar Changsheng Pharmaceutical

US Patent
LigandPNGBDBM444725((S)-1-(3-(3-(4-(1-phenylvinyl)phenyl)-1H- pyrazolo...)
Affinity DataIC50:  55nMAssay Description:Btk kinase activity was determined using a homogenous time resolved fluorescence (HTRF) methodology. Measurements were performed in a reaction volume...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Zibo Biopolar Changsheng Pharmaceutical

US Patent
LigandPNGBDBM444725((S)-1-(3-(3-(4-(1-phenylvinyl)phenyl)-1H- pyrazolo...)
Affinity DataIC50:  55nMAssay Description:Measurements were performed in a reaction volume of 15 μL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 μM peptide subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent