BDBM447663 (3aR,6aR)-5-cyano-N-(5- phenylpyridin-2-yl) hexahydropyrrolo[3,4-b] pyrrole-1(2H)-carboxamide::US10689345, Example 202

SMILES Cc1ccc(NC(=O)N2CC[C@@H]3CN(C[C@H]23)C#N)nc1

InChI Key InChIKey=YPTROWCJXWUAJD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 447663   

TargetUbiquitin carboxyl-terminal hydrolase 30(Human)
Mission Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 447663BDBM447663((3aR,6aR)-5-cyano-N-(5- phenylpyridin-2-yl) hexahy...)
Affinity DataIC50: 100nMAssay Description:USP30 Biochemical Fluorescence Intensity Kinetic Assay.Reactions were performed in duplicate in black 384 well plates (small volume, Greiner 784076) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent