BDBM448800 US10696672, Compound 33::US10696672, Compound 34::US11634418, Compound 33

SMILES OC(=O)[C@H](CCN1CCC(CC1)NC(=O)c1ccc2CCCNc2n1)NC(=O)C1CCC(F)(F)CC1

InChI Key InChIKey=ZUYAPAMZKVQNGG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 448800   

TargetIntegrin alpha-V/beta-6(Human)
Pliant Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 448800BDBM448800(US10696672, Compound 34 | US10696672, Compound 33 ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Microplates were coated with recombinant human integrin αvβ6 (2 ug/ml) in PBS (100 ul/well 25° C., overnight). The coating solution was rem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetIntegrin alpha-V/beta-6(Human)
Pliant Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 448800BDBM448800(US10696672, Compound 34 | US10696672, Compound 33 ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Microplates were coated with recombinant human integrin αvβ6 (2 ug/ml) in PBS (100 ul/well 25° C., overnight). The coating solution was rem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
US Patent

TargetIntegrin alpha-V/beta-6(Human)
Pliant Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 448800BDBM448800(US10696672, Compound 34 | US10696672, Compound 33 ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Microplates were coated with recombinant human integrin αvβ6 (2 ug/ml) in PBS (100 ul/well 25° C. overnight). The coating solution was remo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2023
Entry Details
US Patent