BDBM458676 US10745401, Example 149::US11466007, Example 149

SMILES COc1ccc2c(noc2c1)C1CCN(CCN2CCc3cccnc3C2=O)CC1

InChI Key InChIKey=PBKFFMXSZBEQSD-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 458676   

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458676BDBM458676(US10745401, Example 149 | US11466007, Example 149)
Affinity DataKi:  184nMAssay Description:Present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following procedures. CHO cell membrane ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent

Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458676BDBM458676(US10745401, Example 149 | US11466007, Example 149)
Affinity DataKi:  184nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458676BDBM458676(US10745401, Example 149 | US11466007, Example 149)
Affinity DataKi:  217nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Sumitomo Dainippon Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458676BDBM458676(US10745401, Example 149 | US11466007, Example 149)
Affinity DataKi:  217nMAssay Description:Present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following procedures. CHO cell membrane ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458676BDBM458676(US10745401, Example 149 | US11466007, Example 149)
Affinity DataKi: >1.00E+4nMAssay Description:Present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following procedures. CHO cell membrane ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2022
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Sumitomo Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 458676BDBM458676(US10745401, Example 149 | US11466007, Example 149)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity of the present compound for human 5-HT1A receptor, human 5-HT2A receptor, and human D2 receptor was measured by the following proced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2021
Entry Details
US Patent