BDBM463439 (2S)-2-{[3-amino-1-({4-[(2-oxopyridin-1-yl)methyl]phenyl}methyl)pyrazol-4-::US10781181, Example 116
SMILES C[C@H](NC(=O)c1cn(Cc2ccc(Cn3ccccc3=O)cc2)nc1N)C(=O)N(C)c1cccc(Cl)c1
InChI Key InChIKey=VVRWWUMFOFUNPL-SFHVURJKSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 463439
Affinity DataIC50: >4.00E+4nMAssay Description:KLK1 inhibitory activity in vitro was determined using standard published methods. Human KLK1 (Callbiochem) was incubated at 25° C. with the fluoroge...More data for this Ligand-Target Pair
Affinity DataIC50: 390nMAssay Description:Plasma kallikrein inhibitory activity in vitro was determined using standard published methods. Human plasma kallikrein (Protogen) was incubated at 2...More data for this Ligand-Target Pair