BDBM463566 (S)-2,3-dihydroxy-1-((3S,4S)-3-((R)-1-hydroxyethyl)-4-(4-methoxy-3-((1-(5-(methyl-D3) pyridin-2-yl)azetidin-3-yl)oxy)phenyl)-3-methylpyrrolidin-1-yl)propan-1-one::US10781202, Example 14

SMILES COc1ccc(cc1OC1CN(C1)c1cnc(C)cn1)[C@@H]1CN(C[C@@]1(C)[C@@H](C)O)C(=O)[C@@H](O)CO

InChI Key InChIKey=QWTLPIBEMKNKAM-KAAUDJBISA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 463566   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM463566((S)-2,3-dihydroxy-1-((3S,4S)-3-((R)-1-hydroxyethyl...)
Affinity DataIC50:  0.130nMAssay Description: PDE4A, PDE4B, PDE4C, PDE4D, and PDE5 human recombinant proteins are expressed and purified from Saccharomyes cerevisiae that lack endogenous PDEs. T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent