BDBM463841 2-isopropyl-N,N,4-trimethyl- 8-(6-methyl-7-oxo-6,7- dihydro-1H-pyrrolo[2,3- c]pyridin-4-yl)-3-oxo-3,4- dihydro-2H-1,4-benzoxazine-::US10781209, Example 71

SMILES CC(C)C1Oc2c(cc(c(C)c2N(C)C1=O)S(=O)(=O)N(C)C)-c1cn(C)c(=O)c2[nH]ccc12

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 463841   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM463841(2-isopropyl-N,N,4-trimethyl- 8-(6-methyl-7-oxo-6,7...)
Affinity DataIC50: <100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM463841(2-isopropyl-N,N,4-trimethyl- 8-(6-methyl-7-oxo-6,7...)
Affinity DataIC50: <100nMAssay Description:BRD4-BD1 and BRD4-BD2 assays were conducted in white 384-well polystyrene plate in a final volume of 40 μL for BD1 and 60 μL for BD2. Inhib...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent