BDBM464021 US10787435, Example 009::WX009

SMILES Cc1cc2CCN(C(=O)c2cc1-n1cnc(c1)C1CC1)c1cccc(n1)-c1nnc2CCCCn12

InChI Key InChIKey=YDMAVUBRXNNZMA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 464021   

TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
Fuijan Cosunter Pharmaceutical

US Patent
LigandPNGBDBM464021(US10787435, Example 009 | WX009)
Affinity DataIC50: <50nMAssay Description:Reagents:Base Reaction Buffer: 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35, 0.02 mg/ml BSA, 0.1 mM Na3VO4, 2 mM DTT, 1% DMSOCompound T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent