BDBM464620 CIS-3-(1-Benzoyl-piperidin-4-yl)-1-(cyclopropyl-methyl)-8-dimethylamino-8- phenyl-1,3-diazaspiro[4.5]decan-2-one::US10793556, Example SC_4049::US10793556, Example SC_4050::US10793556, Example SC_4051::US10793556, Example SC_4052::US10793556, Example SC_4053

SMILES CN(C)[C@]1(CC[C@]2(CN(C3CCN(CC3)C(=O)c3ccncc3)C(=O)N2CC2CC2)CC1)c1ccccc1

InChI Key InChIKey=IYJDKQCFKKHBAK-QRRGNZNSSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 464620   

TargetNociceptin receptor(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM464620(CIS-3-(1-Benzoyl-piperidin-4-yl)-1-(cyclopropyl-me...)
Affinity DataKi:  3nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNociceptin receptor(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM464620(CIS-3-(1-Benzoyl-piperidin-4-yl)-1-(cyclopropyl-me...)
Affinity DataKi:  11nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNociceptin receptor(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM464620(CIS-3-(1-Benzoyl-piperidin-4-yl)-1-(cyclopropyl-me...)
Affinity DataKi:  19nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNociceptin receptor(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM464620(CIS-3-(1-Benzoyl-piperidin-4-yl)-1-(cyclopropyl-me...)
Affinity DataKi:  21nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNociceptin receptor(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM464620(CIS-3-(1-Benzoyl-piperidin-4-yl)-1-(cyclopropyl-me...)
Affinity DataKi:  34nMAssay Description:The hNOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl. 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM464620(CIS-3-(1-Benzoyl-piperidin-4-yl)-1-(cyclopropyl-me...)
Affinity DataKi:  175nMAssay Description:The hMOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl (pH 7.4)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM464620(CIS-3-(1-Benzoyl-piperidin-4-yl)-1-(cyclopropyl-me...)
Affinity DataKi:  220nMAssay Description:The hMOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl (pH 7.4)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM464620(CIS-3-(1-Benzoyl-piperidin-4-yl)-1-(cyclopropyl-me...)
Affinity DataKi:  255nMAssay Description:The hMOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl (pH 7.4)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM464620(CIS-3-(1-Benzoyl-piperidin-4-yl)-1-(cyclopropyl-me...)
Affinity DataKi:  770nMAssay Description:The hMOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl (pH 7.4)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM464620(CIS-3-(1-Benzoyl-piperidin-4-yl)-1-(cyclopropyl-me...)
Affinity DataKi:  1.35E+3nMAssay Description:The hMOP receptor binding assay was performed as homogeneous SPA-assay (scintillation proximity assay) using the assay buffer 50 mM TRIS-HCl (pH 7.4)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent