BDBM465482 (3R)-3-(3-(4-(2-fluoro-3- methoxyphenoxy)phenyl)- 7-methoxy-1H-pyrazolo[4,3-c] pyridin-1- yl)cyclohexanecarboxylic acid::US10793566, Compound 121

SMILES COc1cccc(Oc2ccc(cc2)-c2nn(C3CCCN(C3)C(O)=O)c3c(OC)cncc23)c1F

InChI Key InChIKey=AEOYIUAQPLDFOJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 465482   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Zibo Biopolar Changsheng Pharmaceutical

US Patent
LigandPNGBDBM465482((3R)-3-(3-(4-(2-fluoro-3- methoxyphenoxy)phenyl)- ...)
Affinity DataIC50:  55nMAssay Description:Btk kinase activity was determined using a homogenous time resolved fluorescence (HTRF) methodology. Measurements were performed in a reaction volume...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent