BDBM465592 US10793568, Compound I-242

SMILES Cc1cccc(Cl)c1-c1noc(C2CC2)c1CO[C@@H]1C[C@@H]2C[C@H]1CN2c1ccc(CCC(=O)NS(=O)(=O)C2CC2)cc1F

InChI Key InChIKey=QJHCWPHEVYCKBH-RXYILKCJSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 465592   

TargetBile acid receptor(Homo sapiens (Human))
Ardelyx

US Patent
LigandPNGBDBM465592(US10793568, Compound I-242)
Affinity DataEC50:  6.31nMAssay Description:The affinity of FXR ligands for the ligand binding domain of FXR was determined using a commercially available human FXR ligand binding assay (Lantha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent