BDBM466094 US10793580, Example 195::[3-(1-ethyl-8-oxo- spiro[6,7-dihydro-4H- pyrazolo[3,4-c]azepine- 5,4'-tetrahydropyran]-3- yl)-2,2-dimethyl-propyl] 4- ethylbenzoate

SMILES CCc1ccc(cc1)C(=O)OCC(C)(C)Cc1nn(CC)c2c1CC1(CCOCC1)CNC2=O

InChI Key InChIKey=NGRISVMECIVSBJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 466094   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma

US Patent
LigandPNGBDBM466094(US10793580, Example 195 | [3-(1-ethyl-8-oxo- spiro...)
Affinity DataIC50: <100nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [S380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent