BDBM470306 3-(Cyanomethyl)-N-phenyl-3-(4-{3-[3-({[(2,2,2-trifluoroethyl)amino]carbonyl}amino)phenyl]imidazo[1,2-b]pyridazin-7-yl}-1H-pyrazol-1-yl)azetidine-1-carboxamide::US10813930, Ex. No. 84

SMILES FC(F)(F)CNC(=O)Nc1cccc(c1)-c1cnc2cc(cnn12)-c1cnn(c1)C1(CC#N)CN(C1)C(=O)Nc1ccccc1

InChI Key InChIKey=POEPVMLQUMXELJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 470306   

TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 470306BDBM470306(US10813930, Ex. No. 84 | 3-(Cyanomethyl)-N-phenyl-...)
Affinity DataIC50: 10nMAssay Description:FGFR3 Enzymatic Assay The inhibitor potency of compounds of the invention was measured in an enzyme assay that measures peptide phosphorylation using...More data for this Ligand-Target Pair
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Date in BDB:
6/13/2021
Entry Details
US Patent