BDBM472761 US10829492, Example 38::ethyl 2-amino-5-(2-(2,5-difluorophenyl)-4,4-difluoropyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxylate

SMILES CCOC(=O)c1c(N)nn2ccc(nc12)N1CC(F)(F)CC1c1cc(F)ccc1F

InChI Key InChIKey=NWJVGPKPINOTCM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 472761   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM472761(US10829492, Example 38 | ethyl 2-amino-5-(2-(2,5-d...)
Affinity DataIC50: <25nMAssay Description:TrkA, TrkB and TrkC:A testing platform for TrkA, TrkB and TrkC kinase activity was established based on Homogeneous Time-Resolved Fluorescence (HTRF)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent