BDBM472992 4-bromo-6,6a,7,8,9,10-hexahydro-5H- pyrazino[1,2-a][1,8]naphthyridine::US10836764, Compound 136

SMILES Brc1ccnc2N3CCNCC3CCc12

InChI Key InChIKey=WSWQAWOSSYIWCU-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 472992   

Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM472992(4-bromo-6,6a,7,8,9,10-hexahydro-5H- pyrazino[1,2-a...)
Affinity DataKi:  365nMAssay Description:Radioligand binding assays were performed using the commercially available 5-HT2 receptor agonist [125I]DOI as the radioligand and nonspecific bindin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM472992(4-bromo-6,6a,7,8,9,10-hexahydro-5H- pyrazino[1,2-a...)
Affinity DataKi:  966nMAssay Description:Radioligand binding assays were performed using the commercially available 5-HT2 receptor agonist [125I]DOI as the radioligand and nonspecific bindin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM472992(4-bromo-6,6a,7,8,9,10-hexahydro-5H- pyrazino[1,2-a...)
Affinity DataKi:  3.92E+3nMAssay Description:Radioligand binding assays were performed using the commercially available 5-HT2 receptor agonist [125I]DOI as the radioligand and nonspecific bindin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent