BDBM474316 7-(4-fluorophenyl)-8-(3-methylimidazo[l,2-a] pyridin-6-yl )-2-((tetrahydrofuran-3-yl)methyl)-[1,2, 4]triazolo[1,5-c]pyrimidin-5-amine(isomer 2)::US10858365, Compound 105-2
SMILES Cc1cnc2ccc(cn12)-c1c(nc(N)n2nc(C[C@H]3CCOC3)nc12)-c1ccc(F)cc1
InChI Key InChIKey=YEJJJXQNIXCTJY-OAHLLOKOSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 474316
Affinity DataIC50: 0.100nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
Affinity DataIC50: 11.8nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair
Affinity DataIC50: 71.6nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair