BDBM474405 1,1,1,3,3,3-Hexafluoropropan-2-yl 4-(tetrahydro-2H-pyran-3-ylmethyl)-1-oxa-4,9-diazaspiro[5.5]undecane-9-carboxylate ::US10858373, Example 3

SMILES FC(F)(F)C(OC(=O)N1CCC2(CC1)CN(CC1CCCOC1)CCO2)C(F)(F)F

InChI Key InChIKey=CFEDICYKQGDLCA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 474405   

TargetMonoglyceride lipase(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM474405(1,1,1,3,3,3-Hexafluoropropan-2-yl 4-(tetrahydro-2H...)
Affinity DataIC50:  8.49nMAssay Description:T = 30 minutes.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM474405(1,1,1,3,3,3-Hexafluoropropan-2-yl 4-(tetrahydro-2H...)
Affinity DataIC50:  59.9nMAssay Description:Assessment of MAGL inhibition utilizes human recombinant Monoacylglycerol Lipase and the fluorogenic substrate 7-hydroxycoumarinyl arachidonate (7-HC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent