BDBM474407 1-{[(4-Benzyl-1-oxa-4,9-diazaspiro[5.5]undec-9-yl)carbonyl]oxy}pyrrolidine-2,5-dione ::US10858373, Example 5

SMILES O=C(ON1C(=O)CCC1=O)N1CCC2(CC1)CN(Cc1ccccc1)CCO2

InChI Key InChIKey=QUKSFDSMOLTLSL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 474407   

TargetMonoglyceride lipase(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM474407(1-{[(4-Benzyl-1-oxa-4,9-diazaspiro[5.5]undec-9-yl)...)
Affinity DataIC50:  136nMAssay Description:T = 30 minutes.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM474407(1-{[(4-Benzyl-1-oxa-4,9-diazaspiro[5.5]undec-9-yl)...)
Affinity DataIC50:  1.48E+3nMAssay Description:Assessment of MAGL inhibition utilizes human recombinant Monoacylglycerol Lipase and the fluorogenic substrate 7-hydroxycoumarinyl arachidonate (7-HC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent