BDBM474442 US10858373, Example 40

SMILES CN(C1COC2(C1)CCN(CC2)C(=O)OC(C(F)(F)F)C(F)(F)F)S(=O)(=O)c1nccs1

InChI Key InChIKey=ABTCMVPMGZPSEI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 474442   

TargetMonoglyceride lipase(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM474442(US10858373, Example 40)
Affinity DataIC50:  1.43nMAssay Description:T = 30 minutes.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMonoglyceride lipase(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM474442(US10858373, Example 40)
Affinity DataIC50:  22.9nMAssay Description:Assessment of MAGL inhibition utilizes human recombinant Monoacylglycerol Lipase and the fluorogenic substrate 7-hydroxycoumarinyl arachidonate (7-HC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent