BDBM474457 US10881668, Compound 501

SMILES C[C@H](O)CNC(=O)C[C@H]1N=C(c2c(C)c(C)sc2-n2c(C)nnc12)c1ccc(Cl)cc1

InChI Key InChIKey=ZXGRKOXAZLNTEL-APPDUMDISA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 474457   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM474457(US10881668, Compound 501)
Affinity DataIC50:  36nMAssay Description:ssays were performed as described previously with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM474457(US10881668, Compound 501)
Affinity DataIC50:  82nMAssay Description:ssays were performed as described previously with minor modifications from the manufacturer's protocol (PerkinElmer, USA). All reagents were dilu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent