BDBM475678 1-(6-(2-hydroxy-2-(4-methyl-1-oxo- 1,3-dihydroisobenzofuran-5-yl)ethyl)- 5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin- 2-yl)-1H-pyrrolo[3,2-b]pyridine- 3-carbonitrile (Enantiomer-I)::US10851108, Example 68-I
SMILES Cc1c2COC(=O)c2ccc1C(O)CN1CCc2nc(ncc2C1)-n1cc(C#N)c2ncccc12
InChI Key InChIKey=MKUSRPDNOVWCRF-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 475678
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 23nMAssay Description:The coverslip plated with cells was placed in the experiment chamber perfused with bath solution composed of (in mM): 135 NaCl, 5 KCl, 2 CaCl2, 1 MgC...More data for this Ligand-Target Pair