BDBM475841 (1H-Benzotriazol-5-yl)-[(3aS,3bR,6aS,6bR)-5-(4′-fluoro-biphenyl-4-sulfonyl)-octahydro-cyclobuta[1,2-c;3,4-c′]dipyrrol-2-yl]-methanone::US10849881, Example 3

SMILES Fc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N1C[C@H]2[C@@H]3CN(C[C@@H]3[C@H]2C1)C(=O)c1ccc2[nH]nnc2c1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 475841   

TargetAtaxin-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM475841((1H-Benzotriazol-5-yl)-[(3aS,3bR,6aS,6bR)-5-(4R...)
Affinity DataIC50:  173nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent