BDBM475878 3-(4-((3-(2,6-dichloro-2′-(trifluoromethoxy)-[1,1′-biphenyl]-4-yl)ureido)methyl)-3-methylphenyl) acetic acid::US10851050, Example I-34
SMILES Cc1cc(CC(O)=O)ccc1CNC(=O)Nc1cc(Cl)c(c(Cl)c1)-c1ccccc1OC(F)(F)F
InChI Key InChIKey=XZYLMSFNOAHCDQ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 475878
Affinity DataIC50: 398nMAssay Description:Inverse agonist activity at human RORgammat assessed as inhibition of N-terminal biotinylated co-activator SRC1 recruitment measured after 60 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: <500nMAssay Description:The inhibitory activity of compounds on RORγ receptor was determined by fluorescence resonance energy transfer (FRET) experiments. The inhibitor...More data for this Ligand-Target Pair