BDBM478968 (R)-N-(4-(3-((5-chloro-4- methoxypyrimidin-2- yl)amino)pyrrolidine-1-carbonyl)-2- (4-methylpiperazin-1- yl)phenyl)acrylamide::US10894788, Example 73::US10894788, Example 8::US11390618, Example 73
SMILES COc1nc(N[C@@H]2CCN(C2)C(=O)c2cnc(NC(=O)C=C)s2)ncc1Cl
InChI Key InChIKey=CLZRKIMYXQSYDV-SECBINFHSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 478968
Affinity DataIC50: 550nMAssay Description:For the assays, 5 μl solution from each well of the compound dilution plates/10% DMSO were transferred into the assay plates. The final volume o...More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:The IC50 profile of compounds was determined using one protein kinase in a customized, thiol free assay. IC50 values were measured by testing 10 conc...More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:The IC50 profile of compounds was determined using one protein kinase in a customized, thiol free assay. IC50 values were measured by testing 10 conc...More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:For the assays, 5 μl solution from each well of the compound dilution plates/10% DMSO were transferred into the assay plates. The final volume o...More data for this Ligand-Target Pair