BDBM478994 (R)-1-(7-(3-((5-chloropyrimidin-2- yl)amino)pyrrolidine-1-carbonyl)-2H- benzo[b][1,4]oxazin-4(3H)-yl)prop-2- en-1-one::US10894788, Example 34::US10894788, Example 51::US11390618, Example 51
SMILES Clc1cnc(N[C@@H]2CCN(C2)C(=O)c2ccc3N(CCOc3c2)C(=O)C=C)nc1
InChI Key InChIKey=RHCRAQAIFNGFBJ-OAHLLOKOSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 478994
Affinity DataIC50: 550nMAssay Description:For the assays, 5 μl solution from each well of the compound dilution plates/10% DMSO were transferred into the assay plates. The final volume o...More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:The IC50 profile of compounds was determined using one protein kinase in a customized, thiol free assay. IC50 values were measured by testing 10 conc...More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:The IC50 profile of compounds was determined using one protein kinase in a customized, thiol free assay. IC50 values were measured by testing 10 conc...More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:For the assays, 5 μl solution from each well of the compound dilution plates/10% DMSO were transferred into the assay plates. The final volume o...More data for this Ligand-Target Pair