BDBM479537 (R)-3-amino-5-(4-fluorophenyl)-6-(3- methylimidazo[1,2-a]pyridin-6-yl)-N- ((1-methylpyrrolidin-2-yl)methyl) pyrazine-2-carboxamide::US10898481, Compound 138::US11571420, Compound 138

SMILES CN1CCC[C@@H]1CNC(=O)c1nc(-c2ccc3ncc(C)n3c2)c(nc1N)-c1ccc(F)cc1

InChI Key InChIKey=OFCZNIJHHVHDCZ-LJQANCHMSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 479537   

TargetAdenosine receptor A2a(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM479537((R)-3-amino-5-(4-fluorophenyl)-6-(3- methylimidazo...)
Affinity DataIC50:  2.20nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Dizal (Jiangsu) Pharmaceutical

US Patent
LigandPNGBDBM479537((R)-3-amino-5-(4-fluorophenyl)-6-(3- methylimidazo...)
Affinity DataIC50:  17nMAssay Description:Binding affinity and specificalities of the compounds against different subtype of human adenosine receptors (hA1, hA2a, hA2b, and hA3) were characte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM479537((R)-3-amino-5-(4-fluorophenyl)-6-(3- methylimidazo...)
Affinity DataIC50:  2.20nMAssay Description:Binding affinity and specificalities of the compounds against different subtype of human adenosine receptors (hA1, hA2a, hA2b, and hA3) were characte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Dizal (Jiangsu) Pharmaceutical

US Patent
LigandPNGBDBM479537((R)-3-amino-5-(4-fluorophenyl)-6-(3- methylimidazo...)
Affinity DataIC50:  17nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent