BDBM481785 3-(4-chlorophenethyl)-5-((4- methyl-5- oxopyridazino[3,4- d]pyrimidin-6(5H)- yl)methyl)-1,3,4-oxadiazol- 2(3H)-one::US10913742, Example 27

SMILES Cc1cnnc2ncn(Cc3nn(CCc4ccc(Cl)cc4)c(=O)o3)c(=O)c12

InChI Key InChIKey=YLWILSVEXGUUFP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481785   

LigandChemical structure of BindingDB Monomer ID 481785BDBM481785(3-(4-chlorophenethyl)-5-((4- methyl-5- oxopyridazi...)
Affinity DataIC50: 49nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2021
Entry Details
US Patent