BDBM481812 3-(3-(4- methoxyphenyl)cyclobutyl)-5- ((7-methyl-6-oxo-6,7-dihydro- 1H-purin-1-yl)methyl)-1,3,4- oxadiazol-2(3H)-one::US10913742, Example 54

SMILES COc1ccc(cc1)[C@H]1C[C@@H](C1)n1nc(Cn2cnc3ncn(C)c3c2=O)oc1=O

InChI Key InChIKey=ALPYZNHKWLPYPM-HDJSIYSDSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481812   

TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM481812(3-(3-(4- methoxyphenyl)cyclobutyl)-5- ((7-methyl-6...)
Affinity DataIC50:  105nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent