BDBM498187 US11014911, Example 15::US11718603, Example 15

SMILES Cc1cc(CC(=O)Nc2cc([nH]n2)[C@H]2CC[C@H](C2)OC(=O)NC2(C)CC2)on1

InChI Key

Data  12 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 498187   

LigandPNGBDBM498187(US11014911, Example 15 | US11718603, Example 15)
Affinity DataKi:  0.170nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM498187(US11014911, Example 15 | US11718603, Example 15)
Affinity DataKi:  0.170nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM498187(US11014911, Example 15 | US11718603, Example 15)
Affinity DataKi:  6.30nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetCyclin-dependent kinase 9(Human)
Pfizer

US Patent
LigandPNGBDBM498187(US11014911, Example 15 | US11718603, Example 15)
Affinity DataKi:  6.30nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Pfizer

US Patent
LigandPNGBDBM498187(US11014911, Example 15 | US11718603, Example 15)
Affinity DataKi:  16.4nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Pfizer

US Patent
LigandPNGBDBM498187(US11014911, Example 15 | US11718603, Example 15)
Affinity DataKi:  16.4nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM498187(US11014911, Example 15 | US11718603, Example 15)
Affinity DataKi:  26.6nMAssay Description:The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitors by us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM498187(US11014911, Example 15 | US11718603, Example 15)
Affinity DataKi:  26.6nMAssay Description:The purpose CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitors by us...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

US Patent
LigandPNGBDBM498187(US11014911, Example 15 | US11718603, Example 15)
Affinity DataKi:  29.3nMAssay Description:The purpose of GSK3β assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Pfizer

US Patent
LigandPNGBDBM498187(US11014911, Example 15 | US11718603, Example 15)
Affinity DataKi:  29.3nMAssay Description:The purpose of GSK3β assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM498187(US11014911, Example 15 | US11718603, Example 15)
Affinity DataKi:  58.6nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM498187(US11014911, Example 15 | US11718603, Example 15)
Affinity DataKi:  58.6nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent